They also plan to call on the government and the Moro Islamic Liberation Front (MILF) to conclude long-running peace talks and sign a "meaningful and just peace accord."
The peace caravan is due to take off from five key cities and end at the Corregidor Island, west of Manila, where 31 Muslim youths were killed on 18 March 1968.
The massacre is widely considered to have started the now decades long local Muslims struggle for independence.
Mary Ann Arnado, secretary-general of the Mindanao Peoples Caucus (MPC), and the organiser of the peace protest, said they hoped to make the journey "a venue to nationalise" the Mindanao peace agenda.
Manila-based non-governmental organisations and journalists are also expected to take part in the peace protest.
Güncelleme Tarihi: 13 Mart 2008, 16:32