CAIR said "24's" season premier, which shows what the program describe as "Islamic terrorists" detonating a nuclear bomb near Los Angeles, risked stoking racial hatred.
"The raw emotional impact of fictional scenes that include widespread death and destruction in America may adversely affect the public's attitude toward civil liberties, religious freedom and interfaith relations," the group said in a statement.
"The program's repeated association of acts of terrorism with Islam will only serve to increase anti-Muslim prejudice in our society," it added.
The show's network Fox Broadcasting rejected the criticism, claiming that the series didn't single out ethnic groups to be terrorists.
It said villains who appeared during the show's five series included Americans, Baltic Europeans, Germans, Russians, Islamic fundamentalists and the fictional president of the United States.
"The producers are sensitive to the fact that over the course of the series no ethnic group be singled out for persecution or blame," a statement from Fox said.
"In fact, the show has made a concerted effort to show ethnic, religious and political groups as multi-dimensional, and political issues are debated from multiple viewpoints."
CAIR has raised similar concerns about "24" storylines in the past.
In response to a complaint two years ago, Fox aired a public service announcement featuring "24's" star Kiefer Sutherland, urging viewers to avoid stereotyping Muslims.
Güncelleme Tarihi: 20 Eylül 2018, 18:16