A police spokesman described the incident as a suicidal bombing attack.
The wounded were evacuated to nearby hospital and there was no word yet on their condition.
According to eyewitnesses quoted by the Israeli TV, the blast occurred near a restaurant, not far from a bus station.
No Palestinian group has claimed responsibility for the bombing.
Palestinians say human bombings are their only form of deterrent against the Israeli occupation army which routinely raids Palestinian towns and assassinate Palestinian political and resistance activists.
Ten injured in Tel Aviv bombing
Occupied Jerusalem - At least one person was killed and ten others Israelis were injured when a suspected human-bomber blew himself up in down Tel Aviv Thursday.
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