"Investigations have proven that 40 Police Academy students in the third and fourth years belong to the terrorist Brotherhood organization and that they have close relatives who have partaken in the organization's terrorist acts," the agency quoted Interior Ministry spokesman Hani Abdel-Latif as saying.
Abdel-Latif had said earlier during an interview with a private Egyptian satellite channel that political affiliations or active participation in politics violate the police academy's eligibility criteria.
Graduates of the Interior Ministry's police academy are eligible to work in various departments of the country's police apparatus.
Nearly a year ago, the Egyptian government designated the decades-old Brotherhood a "terrorist organization," blaming it for a spate of deadly attacks on security officials in the country.
The move came as part of an ongoing crackdown on the group and its supporters following the military's ouster of president and Brotherhood leader Mohamed Morsi in the summer of last year.
Since then, hundreds of Morsi's supporters have been killed and thousands thrown behind bars.